IndraLab

Statements

USP15 activates epithelial to mesenchymal transition. 15 / 15
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"As shown in our results, knockdown of USP15 resulted in upregulation of E-cadherin and downregulation of N-cadherin and vimentin, while overexpression of USP15 had the opposite effects, suggesting that USP15 can induce EMT in GC cells."
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"Knockdown of USP15 inhibits cell proliferation, invasion, and EMT progression of GC in vitro."
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"The above findings indicated that USP15 may promote cell proliferation, migration, invasion and EMT process to become an oncogene of GC."
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"USP15 promotes cell proliferation, invasion, and EMT progression of GC via regulating the Wnt/β-catenin pathway."
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"Herein, we found that USP-15 enhanced the cell stemness, migration, invasion, and EMT of CRC cells, and USP-15 knockdown led to the opposite results ( Figs."
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"USP15 knockdown significantly impeded cell proliferation, invasion, epithelial-mesenchymal transition, and distal colonization in xenograft models, while enhancing oxaliplatin's antitumor effect."
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"USP15 knockdown significantly inhibited cell proliferation, invasion and epithelial-mesenchymal transition (EMT) of GC in vitro, while overexpression of USP15 promoted these processes."
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"USP15 overexpression promotes cell proliferation, invasion, and EMT progression in GC."
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"USP15 promotes cell proliferation, invasion and EMT progression of GC via regulating the Wnt/beta-catenin pathway, which suggests that USP15 is a novel potential therapeutic target for GC."
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"Furthermore, USP15 promoted cell proliferation, invasion, and EMT progression via the Wnt/β-catenin signaling pathway in vitro and promoted the growth of GC cells in vivo."
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"USP15 knockdown significantly inhibited cell proliferation, invasion and epithelial-mesenchymal transition of GC in vitro, while overexpression of USP15 promoted these processes."
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"USP15 promoted cell proliferation, invasion, and epithelial-mesenchymal transition of GC cells in vitro and tumor growth in vivo."
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"Collectively, these data demonstrated that USP15 overexpression promoted GC proliferation, invasion, and EMT progression."
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"USP15 enhances the tumorigenic effects of TGF-β in glioblastoma (80), while USP4 promotes TGF-β-induced EMT and cell migration in breast cancer."
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"USP15 promoted cell proliferation, invasion, and epithelial-mesenchymal transition (EMT) of GC cells in vitro and tumor growth in vivo."
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