IndraLab

Statements

KCNK18 inhibits MCF2L2. 3 / 3
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"Inhibition of TRESK and other K channels by sanshool robustly increases the firing of DRG mechanoreceptors (Bautista et al., 2008; Lennertz et al., 2010)."
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"In TRESK global knock-out mice, we found that ubiquitous loss of TRESK selectively increased the intrinsic excitability of small-diameter TG nociceptors without affecting DRG neuronal excitability."
31308053
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"TRESK knockout enhances DRG neuron excitability (Tulleuda et al., 2011), and a dominant negative TRESK mutation is implicated in migraine (Lafreniere et al., 2010)."
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