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USP6 deubiquitinates FZD. 2 / 2

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"During the activation of Wnt signaling pathway, USP6 could increase Fzds cell-surface abundance and enhance Wnt by deubiquitylating Fzd [ 9 ]."

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"Conversely, Fzd is deubiquitinated by USP6 and USP8 (Mukai et al. 2010; Jung et al. 2013; Madan et al. 2016)."

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USP6 deubiquitinates FZD. 2 / 2

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