IndraLab

Statements

Myricetin inhibits NLRP3. 5 / 5
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"Myricetin can inhibit apoptosis and autophagy by regulating Nrf2 and NLRP3 pathways, and has a protective effect against lipopolysaccharide-induced acute liver injury in mice [ 37 ]."
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"The increased NLRP3 inflammasome in cells induced by S. aureus was significantly inhibited by myricetin (XREF_FIG)."
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"According to the findings of in vitro AD model (BV-2 microglia cells stimulated with Aβ ), myricetin prevented the hyperactivation of microglia and the conversion from the M2 to the M1 type and inhibited NLRP3 activation by inhibiting the activation of the P38 MAPK signaling pathway."
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"In addition , myricetin ( 75 muM ) inhibited NLRP3 activation by blocking ASC oligomerization in macrophages [ 156 ] ."
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"Myricetin inhibits NLRP3 inflammasome activation via reduction of ROS dependent ubiquitination of ASC and promotion of ROS independent NLRP3 ubiquitination."
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