IndraLab

Statements

(+)-artemisinin inhibits NLRP3. 5 / 5
| 5
reach
"Artemisinin can reduce the oxidative stress reaction due to its NLRP3-regulating ability (47) ."
35252368
reach
"Artemisinin administration suppressed activation of NF-kappaB signaling and the NLRP3 inflammasome in the aorta, likely due to activation of AMP activated protein kinase (AMPK) signaling in aortic macrophages XREF_BIBR."
33643815
reach
"In a transgenic mouse model with AD, artemisinin therapy has been shown to reduce the activity of NLRP3 inflammasomes."
| PMC
reach
"Artemisinin treatment also reduced the neuritic plaque burden and NLRP3 inflammasome activity in an AD transgenic mouse model."
28337127
reach
"Artemisinin can downregulate the NF-kappaB and NLRP3 pathway to attenuate tubulointerstitial fibrosis in subtotal nephrectomized (SNx) rats, which is consistent with the results observed in Ang II treated human kidney 2 (HK-2) cells."
33390969