IndraLab

Statements


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"USP11 upregulates IkappaB kinase alpha in a ubiquitin independent manner XREF_BIBR, while USP18 has been shown to negatively regulate interferon signalling through protein interactions that are independent of its isopeptidase activity XREF_BIBR."

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"Moreover, USP11 knockdown resulted in the reduced production of pro-inflammatory factors and decreased activity of the IKKβ/NF-κB pathway."

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"USP11 positively regulates IkappaB kinase alpha (IKKalpha)."