IndraLab

Statements

NGF increases the amount of SCN10A. 6 / 6
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reach
"We confirm that NGF restores SNS and PN3 mRNA levels in DRG neurons in vitro and demonstrate that the trk antagonist K252a blocks this rescue."
10216225
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"As expected, NGF increased expression of the voltage-gated sodium channel SNS1/PN3 in this system."
11844726
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"TTX-R sodium currents and SNS mRNA expression have been shown to be modulated by nerve growth factor (NGF) in vitro and in vivo."
10036280
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"In the current study, we revealed that; (1) SCI can induce a transition of Na channels from TTX-resistant to TTX-sensitive subtypes, which is at least in part dependent on the increased level of NGF and can be restored by NGF neutralizing treatment, and (2) SCI can induce increased expression of the TTX-sensitive Nav1.7 and decreased expression of the TTX-resistant Nav1.8, which are also restored by NGF neutralizing treatment."
35367467
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"Black et al. (1997) studied an in vitro model that mimics axotomy, and demonstrated that NGF, delivered directly to DRG cell bodies in vitro, down-regulates a-III mRNA and up-regulates SNS/PN3 mRNA ex[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
11098678
reach
"We confirm that NGF restores SNS and PN3 mRNA levels in DRG neurons in vitro and demonstrate that the trk antagonist K252a blocks this rescue."
10216225