IndraLab

Statements

LINC01426 binds USP22. 7 / 7
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"Pull-down sliver staining and RIP assay revealed that LINC01426 could interact with USP22."
33568633
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"LINC01426 binds with USP22 to promote SHH deubiquitination."
33568633
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"Pull-down Silver staining followed by western blot analysis further demonstrated the interaction between LINC01426 and USP22 in PC-9 and Calu3 cells."
33568633
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"Here, we uncovered that LINC01426 could interact with USP22 in LUAD cells."
33568633
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"Here, we determined that LINC01426 interacted with USP22 to stabilize SHH protein."
33568633
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"Researchers have found that LINC01426 enhances the stability of SHH protein by binding to USP22 in tumor tissues, thereby promoting lung adenocarcinoma growth and stemness."
36636053
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"In lung adenocarcinoma (LUAD), LINC01426 recruits and binds the USP22 protein to promote Shh protein stabilization, which activates the Hh pathway and promotes LUAD cells proliferation, migration, and EMT [149]."
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