IndraLab

Statements

Hyaluronic acid inhibits NFKBIA. 3 / 3
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"HA Suppressed IkappaB-alpha Degradation and the Phosphorylation Level of STAT3 and ERK1 / 2 Induced by LPS While the JAK2-STAT3 pathway is essential to regulate the immune response , it is considered to be involved in an `` early '' inflammatory response during sepsis [ 25 ] ."
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"However, our in vivo study found that HA abolished the decrease in densitometric lung tissue cytoplasmic IkappaBalpha concentrations induced by HPV."
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"Moreover , HA significantly inhibited LPS-mediated STAT3 ( Tyr705 ) phosphorylation , IkappaBalpha degradation and ERK1 / 2 activation in THP-1 cells ."
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