IndraLab

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ISG15 bound to USP18 activates USP18. 2 / 2

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"In humans, binding of ISG15 to USP18 prevents USP18 degradation, amplifying the inhibition of IFN signaling."

37115698

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reach

"The binding interaction between free intracellular human ISG15 and USP18 prevents the SKP-2-mediated degradation of USP18."

27887993

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

ISG15 bound to USP18 activates USP18. 2 / 2

INDRA sources:

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