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Cep131 inhibits USP28. 2 / 2

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"We observed biochemical inhibition of USP25 and USP28 by AZ1 with IC 50 s of 3.47 ± 0.73 μM (n = 4) and 0.98 ± 0.02 μM (n = 2) respectively, in line with reported values for the compound."

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"The results showed that AZ1 could effectively inhibit USP28 in non-small cell lung cancer (Fig. xref A)."

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Cep131 inhibits USP28. 2 / 2

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