IndraLab

Statements

SIAH2 binds USP19. 7 / 7
4 | 2 1
biogrid
No evidence text available
23500468
reach
"To assess whether USP19 interacts with SIAH1 and SIAH2 in eukaryotic cells, HEK293T cells were co-transfected with plasmids expressing Myc-USP19 and HA-SIAH1 or HA-SIAH2 and cell lysates were subjecte[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
23500468
reach
"Probing Western blots of anti-Myc immunoprecipitates with an anti-HA antibody confirmed that USP19 interacts with both SIAH1 and SIAH2."
23500468
biogrid
No evidence text available
23500468
biogrid
No evidence text available
22128162
biogrid
No evidence text available
22128162
sparser
"SIAH2 binds to USP19 and promotes USP19 ubiquitylation and proteasome‐dependent degradation xref ; then, the hypothesis of a causal link between SIAH2 and USP19 in cardiomyocyte hypertrophy was established: Decreased transcription of SIAH2 during hypertrophic progress led to less degradation of USP19, and this mechanism partially accounted for USP19 elevation."
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