IndraLab

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OTUB1 leads to the deubiquitination of RAB8A. 3 / 3
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"Our findings indicated that overexpression of circ_0 005185 led to a reduction in RAB8A ubiquitination, whereas knockdown of OTUB1 increased RAB8A ubiquitination (Figures 4E,F and S1D,E, Supporting Information)."
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"21 , 22 , 23 However, the potential interaction between OTUB1 and RAB8A and the mechanism by which OTUB1 promotes RAB8A deubiquitination have not been reported.2 Results."
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"Thus, it is hypothesized that OTUB1 promotes the deubiquitination of RAB8A, thereby regulating its protein levels."
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