IndraLab

Statements

USP5 inhibits CTNNB1. 3 / 3
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eidos
"Taken together , these findings indicated that USP5 prevented beta-catenin degradation by inhibiting its ubiquitination and regulated the Wnt / beta-catenin signaling pathway to promote EMT in NSCLC cells ."
32477134
reach
"Targeting USP5 with the small molecule WP1130 induced the degradation of β-catenin, and showed markedly inhibitory effects on tumor growth and metastasis [122]."
38872189
reach
"Targeting USP5 with the small molecule WP1130 promoted the degradation of beta-catenin, and showed great inhibitory effects on sphere formation, migration, and invasion."
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