IndraLab

Statements


ATP inhibits RELA. 6 / 6
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"Extracellular ATP activates transcription factor NF-kappaB through the P2Z purinoreceptor by selectively targeting NF-kappaB p65."

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"Extracellular ATP acting via the P2X 7 receptor activates the transcription factor NFkappaB by selectively targeting NFkappaB p65 (Rel A) in the N9 mouse microglial cell line [XREF_BIBR]."

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"ATP decreased the binding of p65 to potential sites in the OPN promoter region in NPC cells."

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"Extracellular ATP acting via the P2X 7 receptor activates the transcription factor NF-kappaB by selectively targeting NF-kappaB p65 (Rel A) in the N9 mouse microglial cell line [XREF_BIBR]."

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"Using a ChIP assay, we further found that ATP could lower the binding of p65 to potential sites in the OPN promoter region."

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"As P2Y2 might be involved in the ATP induced downregulation of p65 and OPN, we further examined the effect of P2Y2 on the level of p65 and OPN by western blotting."