IndraLab

Statements

KCNMA1 activates immune response. 6 / 6
| 6
reach
"Protective immunity is mediated by neutralization of active SLO."
23300245
reach
"A non toxic SLO derivate elicits protective immunity against lethal GAS challenge in a murine infection model."
26635795
reach
"SLO toxin can prevent neutrophil degranulation and elicit further protective immunity if administered in subcytotoxic concentrations (56)."
37588093
reach
"Taken together, these results indicate that less toxic SLO variants that produce strands and altered pores could promote a more robust immune response through enhanced cytokine secretion."
23744055
reach
"A multivalent non-M protein vaccine, VAX-A1 composed of SpyAD-GAC , SCPA, and SLO antigens stimulated systemic immunity with the goal of broad protection of GAS strains without autoreactivity following the intravenous administration route in mice [110]."
38543906
reach
"SLO maintains immune homeostasis and promotes a rapid and effective immune response (83)."
35990622