IndraLab

Statements


USP18 inhibits IFNG. 2 / 2
| 2

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"USP18 inhibition by two independent siRNAs increased beta cell apoptosis following exposure to IFNalpha or IFNgamma (XREF_FIG), whereas siCTRL has no such effect."

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"The absence of Usp18 limited the expansion of virus specific CD8 + T cells (XREF_FIG) and reduced IFN-gamma production by CD8 + T cells (XREF_FIG) and CD4 + T cells (XREF_FIG)."