IndraLab

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Trans-piceid inhibits NLRP3. 6 / 6
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"This could be of potential therapeutic relevance.In earlier reports, polydatin suppresses NLRP3 inflammasome activation and ameliorates potassium oxonate induced kidney inflammation in rats [20], and [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Polydatin can inhibit the activation of the NLRP3 inflammasome and cleavage of caspase-1, thereby inhibiting pyroptosis and secretion of inflammatory cytokines, and promoting autophagy through NLRP3/mTOR pathway in AS."
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"In mice infected with Mycoplasma pneumomiae, polydatin treatment can suppress NF-kappaB and NLRP3 signaling pathway activation, thereby attenuating lung inflammation and fibrosis."
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"Polydatin Inhibits NLRP3 Inflammasome in Dry Eye Disease by Attenuating Oxidative Stress and Inhibiting the NF-kappaB Pathway."
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"In earlier reports, polydatin suppresses NLRP3 inflammasome activation and ameliorates potassium oxonate induced kidney inflammation in rats XREF_BIBR, and enhances PPAR-alpha and inhibits SCD-1 in animal models induced by streptozocin or a high-fat diet XREF_BIBR, XREF_BIBR."
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"In addition, the hyperosmolar stress induced NLRP3 inflammasome pathway and ROS production were inhibited by polydatin."
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