IndraLab

Statements

USP45 increases the amount of MKI67. 2 / 2
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"USP45 knockdown significantly inhibited the growth rate and weight of tumors and the protein expression of cyclin D1, Ki-67, and PCNA in nude mice (Fig. 1I)."
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"Furthermore, the effect of USP45 on cell proliferation was also confirmed by Western blot, which showed that overexpression of USP45 up-regulated the expression of cyclin D1, Ki-67, and PCNA (Fig. 1F), while knockdown of USP45 down-regulated cyclin D1, Ki-67, and PCNA (Fig. 1G)."
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