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USP22 increases the amount of TFRC. 2 / 2

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"These findings collectively demonstrated that USP22 negatively regulates ferroptosis in hepatocellular carcinoma cells.2.6 USP22 modulates cellular H2BK120ub level and the transcription of TFRC ."

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"In summary, these findings suggested that USP22 knockout enhances the occupation of H2BK120ub on the TSS downstream region of TFRC, thereby promoting TFRC transcription.2.7 USP22 inhibits Sorafenib-induced ferroptosis through downregulating TFRC transcription."

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USP22 increases the amount of TFRC. 2 / 2

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