IndraLab

Statements


EIF3H increases the amount of SNAI1. 5 / 5
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"The interaction between EIF3H and Snail suggests the ability of EIF3H to regulate Snail expression."

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"Expression of Snail and EIF3H was detected (left) and the intensity of Snail expression was quantified by Image J software (right).cSnail-Flag, HA-UB plasmids with or without EIF3H were co-transfected in HEK293T cells for 24 h. After another 4 h 10 muM MG132 incubation, the ubiquitination assay was performed to detect the poly-ubiquitination of Snail.dandeThe CHX pulse-chase assay was performed on EIF3H stably overexpressed in KYSE150 and KYSE510 cells."

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"Clinically, the levels of EIF3H were positively correlated with Snail expression."

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"In concordance with our findings in xenograft model, the expression levels of EIF3H were positively correlated with Snail expression in the ESCC tissue samples (Fig.7c)."

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"The Snail and EIF3H expression were analyzed by immunoblotting (left panel)."