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PCNA deubiquitinates USP1. 2 / 2

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"To provide additional confirmation, we aimed to test the effect of decreasing the level of ubiquitin conjugated PCNA, which can be carried out by expressing the PCNA deubiquitylating enzyme USP1 as described."

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"XREF_BIBR The levels of PCNA modification are additionally controlled by the clamp loader Elg1, which binds to and unloads sumoylated PCNA from chromatin in yeast XREF_BIBR and targets the PCNA deubiquitinating enzyme USP1 to replicative DNA lesions in humans."

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PCNA deubiquitinates USP1. 2 / 2

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