IndraLab

Statements



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"USP1 Promotes GC Metastasis via Stabilizing ID2."

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"USP1 dependent RPS16 protein stability drives growth and metastasis of human hepatocellular carcinoma cells."

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"USP1 inhibition destabilizes KPNA2 and suppresses breast cancer metastasis."

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"In conclusion, our study showed that USP1 promoted GC metastasis via stabilizing ID2 expression, which provides a potential biomarker and therapy target for GC."

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"Mechanically, we demonstrated that USP1 promoted GC metastasis via upregulating ID2 expression and further confirmed that USP1 stabilized ID2 expression through deubiquitinating ID2 in GC."

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"Then, real-time cellular analysis (RTCA) showed that USP1 knockdown inhibited GC metastasis both in vitro and in vivo."