IndraLab

Statements

Wedelolactone inhibits CHUK. 6 / 7
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sparser
"Moreover, inhibition of IKKα by wedelolactone decreases the nuclear localization of AR and suppresses AR signaling xref ."
29142311
sparser
"Wedelolactone also inhibits both IKKα and IKKβ through modulation of caspases and IκB phosphorylation ( xref )."
23455325
sparser
"To determine if the rapid induction of apoptosis in macrophages and DC was NF-κB/IKK inhibition-dependent and not an off-target effect of TAT-NBD, five additional NF-κB inhibitory compounds were tested: Compound A (CmpA) and TPCA-1, both of which inhibit IKKβ; MG-132, which inhibits IκBα proteosomal degradation; and IKKiVII and Wedelolactone, which inhibit both IKKα and IKKβ (see xref )."
24406986
reach
"Moreover, inhibition of IKKalpha by wedelolactone decreases the nuclear localization of AR and suppresses AR signaling 29."
29142311
sparser
"As expected, staurosporine inhibited all kinase activity, and wedelolactone selectively inhibited IKKα and IKKβ."
29374256
reach
"As expected, staurosporine inhibited all kinase activity, and wedelolactone selectively inhibited IKKalpha and IKKbeta."
29374256