IndraLab

Statements


TP53 bound to NOC2L activates TP53. 2 / 2
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reach
"In addition, p53 can associate with the novel INHAT repressor (NIR), which reduces p53 dependent transcription under normal growth conditions and in response to cellular stress."

reach
"NIR (novel INHAT repressor) can bind to p53 at promoters and inhibit p53 mediated gene transactivation by blocking histone acetylation carried out by p300 and CBP."