IndraLab

Statements

Dihydrogen inhibits NLRP3. 13 / 13
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"Hydrogen Rich Saline Inhibits NLRP3 Inflammasome Activation and Attenuates Experimental Acute Pancreatitis in Mice."
25214720
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"Moreover, hydrogen inhibited the nuclear factor erythroid 2-related factor 2 (Nrf2)-mediated NLRP3 pathway, which alleviated inflammation, neuronal apoptosis, and mitochondrial dysfunction, as shown in [75]."
37891821
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"In an in vitro study, ROS inhibitors blocked priming, but not activation of the NLRP3 inflammasome XREF_BIBR, which may support that hydrogen rich water can not block activation of NLRP3 inflammasomes."
24985521
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"On the one hand, hydrogen can stimulate a specific nucleotide-bearing domain and inhibit NLRP3 in macrophages and limit inflammatory reactions [88,105]."
36978884
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"We demonstrated that hydrogen might reduce NLRP3-mediated cardiomyocytes pyroptosis by inhibiting oxidative stress, thereby reducing myocardial injury and improving cardiac function."
34400901
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"Hydrogen promoted autophagy related protein expression, inhibited the inflammasome NLRP3 pathway activation, and relieved the hyperpathia induced by neuropathic pain."
31689487
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"Hydrogen Rich Saline Attenuated Subarachnoid Hemorrhage Induced Early Brain Injury in Rats by Suppressing Inflammatory Response : Possible Involvement of NF-kappaB Pathway and NLRP3 Inflammasome."
26091790
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"Hydrogen Attenuates Myocardial Injury in Rats by Regulating Oxidative Stress and NLRP3 Inflammasome Mediated Pyroptosis."
34400901
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"Thus, it is necessary to explore whether hydrogen gas inhalation can reduce NLRP3 inflammasome and mitigate this downstream effects after SAH."
32038143
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"XREF_BIBR A current investigation reported that hydrogen could inhibit the activation of NLRP3 inflammasome in AD brains."
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"Recently, hydrogen rich saline was reported to attenuate EBI by repressing NLRP3 and NF-κB related inflammation (Shao et al., 2016)."
32038143
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"Molecular hydrogen can also inactivate the NLRP3 inflammasome through the activation of autophagy and mitigation of mitochondrial dysfunction and cytokine release in septic mice (Chen et al. 2019)."
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"First, although we demonstrated that hydrogen could reduce activation of the NLRP3 inflammasome and improve cardiac function and remodeling after AMI, it is unknown whether NLRP3 plays a causal role."
34400901