IndraLab

Statements

Dihydrogen inhibits NLRP3. 15 / 15
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"Recently, hydrogen rich saline was reported to attenuate EBI by repressing NLRP3 and NF-κB related inflammation (Shao et al., 2016)."
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"Hydrogen inhibits endometrial cancer growth via ROS/ NLRP3/caspase-1-mediated pyroptotic pathway [15] ."
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"Hydrogen Rich Saline Attenuated Subarachnoid Hemorrhage Induced Early Brain Injury in Rats by Suppressing Inflammatory Response : Possible Involvement of NF-kappaB Pathway and NLRP3 Inflammasome."
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"First, although we demonstrated that hydrogen could reduce activation of the NLRP3 inflammasome and improve cardiac function and remodeling after AMI, it is unknown whether NLRP3 plays a causal role."
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"Hydrogen Rich Saline Inhibits NLRP3 Inflammasome Activation and Attenuates Experimental Acute Pancreatitis in Mice."
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"Our findings have, for the first time, revealed the novel mechanism underlying the inhibitory effect of molecular hydrogen on LPS caused NLRP3 inflammasome activation, highlighting the promising application of this new antioxidant in the treatment of LPS associated inflammatory pathological damage."
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"XREF_BIBR A current investigation reported that hydrogen could inhibit the activation of NLRP3 inflammasome in AD brains."
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"Thus, it is necessary to explore whether hydrogen gas inhalation can reduce NLRP3 inflammasome and mitigate this downstream effects after SAH."
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"Hydrogen Attenuates Myocardial Injury in Rats by Regulating Oxidative Stress and NLRP3 Inflammasome Mediated Pyroptosis."
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"Molecular hydrogen can also inactivate the NLRP3 inflammasome through the activation of autophagy and mitigation of mitochondrial dysfunction and cytokine release in septic mice ."
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"We demonstrated that hydrogen might reduce NLRP3-mediated cardiomyocytes pyroptosis by inhibiting oxidative stress, thereby reducing myocardial injury and improving cardiac function."
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"Molecular hydrogen inhibits lipopolysaccharide triggered NLRP3 inflammasome activation in macrophages by targeting the mitochondrial reactive oxygen species."
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"In an in vitro study, ROS inhibitors blocked priming, but not activation of the NLRP3 inflammasome XREF_BIBR, which may support that hydrogen rich water can not block activation of NLRP3 inflammasomes."
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"Molecular hydrogen can also inactivate the NLRP3 inflammasome through the activation of autophagy and mitigation of mitochondrial dysfunction and cytokine release in septic mice (Chen et al. 2019)."
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"Hydrogen promoted autophagy related protein expression, inhibited the inflammasome NLRP3 pathway activation, and relieved the hyperpathia induced by neuropathic pain."
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