IndraLab

Statements

USP5 activates IFNB1. 2 / 2
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reach
"Statistical significance was set at a p < 0.05.To investigate how USP5 is involved in the IFNs antiviral activity, we firstly examined whether USP5 affects the virus-induced IFN-β activation."
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reach
"In contrast, USP5 which shares 80% sequence similarity with USP13, neither interacted with STING in an overexpression system nor inhibited cGAS and STING induced activation of IFN-beta promoter in reporter assays (XREF_FIG), indicating a specific interaction between USP13 and STING."
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