IndraLab

Statements


OTULIN inhibits Mice. 4 / 4
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"64 Specific OTULIN deficiency can cause chronic liver inflammation and cancer in mice."

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"OTULIN deficiency also increases intestinal pathology in mice genetically engineered to secrete excess TNF, confirming that chronic exposure to TNF promotes epithelial cell death and inflammation in OTULIN deficient mice."

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"OTULIN deficiency increases intestinal pathology in TNF emARE mice."

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"OTULIN inhibits RIPK1-mediated keratinocyte necroptosis to prevent skin inflammation in mice."