IndraLab

Statements

KCNH1 activates CD4. 2 / 2
| 2
reach
"Taken together, our data suggest that LFA-1 is not required for EAg induced activation of CD4 + T-cells in vitro or in vivo but is required for trafficking of T-cells to the MLNs and homing of colitogenic effector cells to the colon where they initiate chronic gut inflammation."
22488891
reach
"We found that EAg pulsed dendritic cells (DCs) induced proliferation of LFA-1-deficient (CD11a -/-) CD4 + T-cells that was very similar to that induced using WT T-cells suggesting that LFA-1 is not required for activation and proliferation of T-cells in vitro."
22488891