IndraLab

Statements

USP19 activates FLVCR1. 2 / 2
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"Reports indicate that the disruption of USP19 inhibits a series of PCa cell proliferation by arresting cells in the G1 to S phase transition through stabilization of the cyclin-dependent kinase inhibitor p27 ."
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"The knockdown of the USP19 gene could inhibit the progression of PCa in two ways; first, by causing defects in cell cycle progression and delaying the progression from G0/G1 to S phase, and second, by accumulating p27 and inhibiting the ability of USP19 to regulate cell growth (Lu et al., 2011)."
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