IndraLab

Statements

UCHL3 activates cell migration. 9 / 9
| 9
reach
"In conclusion, the findings suggest that UCHL3 promotes HCC cell migration through stabilizing Vimentin."
36969045
reach
"UCHL3 promoted HCC cell migration and stem-like properties.Cell migration and stem-like properties contribute to the aggressiveness of tumors and poor patient prognosis (43)."
36969045
reach
"UCHL3 promotes hepatocellular carcinoma cell migration by de-ubiquitinating and stabilizing Vimentin."
36969045
reach
"Our results show that UCH-L3 overexpression induced the expression of stemness genes (OCT4, SOX2, ZEB2, and MMP2), and increased cell migration (Figs."
37460253
reach
"Vimentin attenuated the suppression of cell migration caused by knockdown of UCHL3."
36969045
reach
"UCHL3 overexpression promoted cell migration during wound healing ( Figure 2C ) and Transwell assays ( Figure 2D )."
36969045
reach
"UCHL3 knockdown inhibited cell migration and stem-like properties, as revealed by wound healing and Transwell assays ( Figures 3C, D ) and spheroid formation assays ( Figure 3E )."
36969045
reach
"In addition, UCHL3 overexpression promoted EJ cell migration, but no alteration in EJ cell migration was observed when the deubiquitination-catalyzing site in UCHL3 was mutated (Fig. 1E)."
37740194
reach
"Therefore, the biological function of UCHL5 requires more investigation.One recent study reported that UCHL3 promotes GC cell migration and invasion by upregulating IGF2 [85]."
36497313