IndraLab

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"In addition, SB203580 reversed the p-p38 up-regulation and p65 NF-κB nuclear translocation in lung tissues of LPS-induced mice (all P < 0.05); meanwhile, PDTC also reduced p65 NF-κB in nuclear without[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"The LPS induced phosphorylation of MAPKs (p38, JNK and ERK1/2) and NF-kappaB p65 was also strongly inhibited by their inhibitors SB203580, U0126, SP600125 and PDTC, respectively."

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"Thus, we investigated the effect of ET-1 stimulation versus up- (Chrysin), and downregulation (SB203580) of p38 as well as p65 upregulation (MG132) on these target genes."

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"By contrast, when NPCs were treated with Bay 11-7082 (inhibitor of p65 NF-kB), SB203580 (inhibitor of p38 MAPK), U0126 (inhibitor of ERK), and SP600125 (inhibitor of JNK) in the presence or absence of[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"Twenty micromolar SP600125 and 10 muM SB203580 reduced the lipopolysaccharide caused increase in the NF-kappaB p65 to DNA binding activity in HaCaT cells."

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"Microinjection of p38 inhibitor SB203580 into the NAc prior to the application of morphine prevented the acquisition of CPP and inhibited the activation of p38, IkappaB-alpha and NF-kappaB p65."