IndraLab

Statements

OTUD5 activates Interferon. 2 / 3
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reach
"In the presence of CD-associated NOD2 mutations, impaired recognition of MDP results in inefficient induction of DUBA, which leads to excessive and colitogenic type I IFN and Th1 responses upon TLR9 activation ( Figure 4B )."
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reach
"Among identified candidates were known regulators of IFN signaling such as Usp25 ( Lin et al., 2015 ), Usp15 ( Pauli et al., 2014 ), and DUBA, which displayed reduced expression in H1N1-infected cells[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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