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USP25 increases the amount of IL33. 2 / 2

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"Their results demonstrated that USP21 promotes the transcription of p65 via deubiquitylation and stabilization of IL-33, which functions as a transcriptional regulator of p65 and induces the expression of intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 through its regulatory effect on the NF-κB pathway in endothelial cells (Choi et al., 2012; Tao et al., 2014)."

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"Here, we show that USP21 mediated deubiquitination of IL-33 affects the transcription of p65."

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IndraLab

Statements

USP25 increases the amount of IL33. 2 / 2

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