IndraLab

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Atx7 inhibits USP22. 2 / 2

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"Moreover, polyQ expansion of Atx7 decreases the deubiquitinating activity of USP22 and, consequently, increases the level of monoubiquitinated H2B."

26195632

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"The mutation of the zinc finger domain in Atx7 that disrupts its interaction with USP22 dramatically abolishes sequestration of USP22."

26195632

INDRA sources:

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IndraLab

Statements

Atx7 inhibits USP22. 2 / 2

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