IndraLab

Statements

Unubiquitinated USP18 increases the amount of FTO. 3 / 3
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"Song et al. (2021b) showed that USP18 post-translational deubiquitination up-regulates FTO protein expression, while FTO promotes BC occurrence and progression via its demethylase activity on PYCR1 to stabilize its transcript."
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"Song et al. (Song et al., 2021), for the first time, reported that the post-translational deubiquitination of USP18 could upregulate FTO protein expression and stability."
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"Song et al. found that post-translational deubiquitination of USP18 upregulates FTO protein expression, whereas FTO promotes the occurrence and development of BCa through its demethylase activity on PYCR1 and stabilizes its transcript [207]."
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