IndraLab

Statements


ATM activates USP10. 3 / 5
2 | 2 1

reach
"As shown, both AKT and ATM increase the activity of USP10."

reach
"However, upon exposure to external stress such as high concentrations of hydrogen peroxide [65], the inhibition of USP10 by G3BP1 is abrogated and USP10 is induced to phosphorylate by ataxia-telangiectasia-mutated protein (ATM) or activated by ATM-phosphorylated protein, thereby reducing ROS production and apoptosis [64]."

sparser
"ROS-induced stress promotes ATM-dependent USP10 activation."