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"Illustrative of genetic vulnerability maps of brain function based on imaging genetics approaches, Rasetti et al reviewed neuroimaging intermediate phenotypes of schizophrenia and the gene variants associated with them, catalogued by cognitive task. xref For example, working memory tasks have revealed abnormal engagement of: dorsolateral prefrontal cortex associated with CACNA1C, COMT, GAD1, GRM3, DRD2, KCNH2, MTHFR, and RGS4; ventrolateral prefrontal cortex associated with COMT, PRODH, and RGS4; thalamus and hippocampus associated with NRG1, DAOA/G72, and DISCI; and parietal lobe associated with PRODH."