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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Lipopolysaccharide activates OTUD5. 3 / 3

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"As DUBA protein is also increased in macrophages by LPS stimulation, it may also function as part of a negative feedback circuit."

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"As OTUD5 is induced by LPS stimulation , it might act as a negative feedback regulator of IFN signaling by targeting TRAF3 [ 119 ] ."

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"As DUBA protein is also increased in macrophages by LPS stimulation, it may also function as part of a negative feedback circuit.Another OTU DUB family protein, the tumor suppressor, CYLD, has been identified as a negative regulator of RIG-I by two groups [61, 62] ."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...