IndraLab

Statements

OTUB1 inhibits Neoplasm Invasiveness. 3 / 3
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"OTUB1 restrains the expression of some proinflammatory gene (such as CXCL10, CXCL11, CCL2 and NOS2) in astrocytes, and inhibits the invasion of encephalitogenic T cells in the spital cord during EAE."
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"Knockdown of OTUB1 inhibited cell viability and proliferation, as well as migration and invasion of RCC cells."
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"The trans-well assay showed that OTUB1 knocking-down inhibited cell invasion capacity in AGS and MKN28 cells (Fig. 3K), while the clone formation assay showed that OTUB1 depletion could significantly reduce the numbers of clones in AGS and MKN28 cells (Fig. 3L)."
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