IndraLab

Statements


UCHL1 deubiquitinates SNCA. 2 / 2
1 | 1

"The deubiquitination of α-synuclein aggregates by USP9X favor their degradation by autophagy, while UCH-L1 contribute to the accumulation of α-synuclein by downregulating its lysosomal degradation."

reach
"No clear substrates have been described for UCHL1 in vivo, but UCHL1 may deubiquitinate alpha-synuclein."