IndraLab

Statements

USP3 deubiquitinates Histone-H2A. 3 / 3
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"RNF168 is an E3 ligase that ubiquitinates histones H2A and gammaH2AX during the DNA damage response [XREF_BIBR], this ubiquitination can be reversed by Usp3 [XREF_BIBR]."
25962961
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"Deubiquitination of histones H2A and H2B by USP3 is required for progression through the S phase and for genomic stability."
22941662
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"Several DUBs have been implicated in histone deubiquitination, including USP3, USP12, USP22, and USP46, which deubiquitinate both histones H2A and histones H2B [XREF_BIBR]."
33327527