IndraLab

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SIRT7 deacetylates USP39. 6 / 6
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"SIRT7 interacts with and mediates USP39 deacetylation."

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"In addition, SIRT7 deacetylates USP39 to promote its protein stability and enhance autophagy, while inhibiting ROS production in CSCC cells [33]."

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"A previous study suggested that SIRT7 promoted the deacetylation of USP39 in hepatocellular carcinoma cells [24]."

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"USP39 was deacetylated by SIRT7 and promoted SIRT7 expression by facilitating FOXM1-mediated SIRT7 transcription."

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"The de-acetylation of USP39 by SIRT7 can promote its stability and thereby accelerate HCC cell proliferation and tumorigenesis."

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"The deacetylation of USP39 by SIRT7 promotes the stability and thereby accelerates cell proliferation and tumorigenesis of HCC [10] ."