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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP35 inhibits ubiquitination. 1 / 1

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"USP35 regulates the Aurora B protein levels during mitosis without affecting the localization of Aurora B. In other words, USP35 inhibits APC/C-CDH1-induced ubiquitination of Aurora B by cleaving Lys11-linked polyubiquitin chains and prevents it from proteasomal degradation ( xref d)."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...