IndraLab

Statements


GstD1 activates PRPF8. 1 / 1
| 1

reach
"Furthermore, gstD1-GFP and p53 upregulation was also observed in imaginal disc cells overexpressing the pathogenic RP13-linked mutant variant of Prp8 protein (Drosophila Prp8 /human PRPF8 ) (Supplementary Figure 1H–M), suggesting a shared response to U5 snRNP malfunction, inflicted either by scarcity of the biogenesis factor or mutation in the core splicing factor."