IndraLab

Statements

USP19 increases the amount of DDIT3. 3 / 3
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"The higher levels of CHOP mRNA seen during regeneration in the USP19 KO muscle suggest that USP19 modulates transcription of CHOP, but modulation of CHOP mRNA stability can not be excluded."
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"First, USP19 (XREF_FIG) modulated the expression of CHOP, which had previously been shown to be the key marker of the ER stress response that occurs in only a small fraction of the differentiating myoblasts but is critical for differentiation."
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"The mechanisms by which CHOP expression is modulated by USP19 will require further study."
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