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OTUD7B deubiquitinates p53.Finally. 1 / 1

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"Together these findings establish that OTUD7B functions to de-ubiquitinate wildtype and mutant forms of p53.Finally, to ascertain the type of ubiquitin modification present in p53 removed by OTUD7B, we repeated the ubiquitination assay after transfecting a series of ubiquitin mutants (K6, K11, K27, K29, K33, K48 and K63) where all but one lysine had not been mutated (Figure 4G)."

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IndraLab

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OTUD7B deubiquitinates p53.Finally. 1 / 1

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