IndraLab

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USP53 inhibits Neoplasm Invasiveness. 7 / 7
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"Therefore, it can be explained that the gene USP53 can inhibit the migration and invasion of renal cancer cells."
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"Furthermore, the ectopic expression of USP53 inhibited the proliferation, migration and invasion, and induced the apoptosis of HCC cells."
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"Furthermore, forced expression of USP53 inhibited the proliferation, migration and invasion, and induced apoptosis in HCC cell lines both in vitro and in vivo."
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"In the study of USP53-mediated IκB stabilization, researchers found that USP53 inhibits the proliferation, invasion, and migration of renal cancer cells in vitro and in vivo (53)."
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"The results showed that USP53 knockdown significantly promoted the migration and invasion of renal cancer cells Caki‐1 and 786‐O cells (Figure 5C,D)."
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"Wound-healing and transwell assays showed that the overexpressed USP53 significantly inhibited the migration (Fig. 2D–G) and invasion (Fig. 2H, I) of HCC cells in vitro."
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"EDU cell proliferation imaging assay and BrdU cell proliferation assay also showed that the proliferation of ccRCC after USP53 knockdown was promoted compare with shGFP (Figure 3E–H).3.4 Overexpression USP53 inhibits migration and invasion of ccRCC."
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