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Temsirolimus activates ATXN3. 1 / 1

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"However, consistent with mTOR inhibition inducing autophagy, ataxin-3 transgenic mice treated with temsirolimus showed decreased levels of phosphorylated S6 ribosomal protein (a downstream target of the mTOR pathway), and levels the mutant protein in the cytosol were decreased, as were the number of aggregates."

20007218

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Temsirolimus activates ATXN3. 1 / 1

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