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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Ubiquitin inhibits BAP1. 2 / 2

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"The fact that an ubiquitin conjugate can inhibit BAP1 to a greater extent than ubiquitin alone, illustrates how this DUB prefers binding its target (ubiquitin conjugate) over its product (ubiquitin alone)."

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"ASXL1 WT could induce H2AK119 ubiquitination (Ub) through negatively regulating BAP1 which removes ubiquitination of H2AK119 as a deubiquitinase (Fig. 2b)."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...